Modelling predictive gender- and gestation-specific weight reference centiles for preterm infants using a population-based cohort study.

ABSTRACT: We aimed to model longitudinal data to create predictive growth charts for weight in preterm infants from birth till discharge, that took into account the differing growth rates post-birth when compared to in-utero growth and therefore was more representative of the data than the UK1990 reference charts. Data from birth until discharge (or death), was collected and rigorously cleaned for all infants born at <32 weeks of gestation over a 4-year period. Means and standard deviations from the UK1990 reference charts were used to compute standard deviation scores (SDS) for our cohort. 2/3rd of the data was randomly selected and used to create gestation and gender-specific predictive weight centile lines through novel application of mixed modelling methods. The remaining 1/3rd of the data was u

SUBMITTER: Watkins WJ 

PROVIDER: S-EPMC7055271 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature