Optimal endoscopy timing in patients with acute variceal bleeding: A systematic review and meta-analysis.

ABSTRACT: Although current guidelines recommend performing endoscopy within 12 hours for acute variceal bleeding (AVB), the optimal timing remains controversial. This study aimed to assess the effect of endoscopy timing on the mortality and rebleeding rates in AVB through a systematic review and meta-analysis of all eligible studies. PubMed, Cochrane Library, and Embase were searched for relevant publications up to January 2019. Overall mortality, rebleeding rate, and other clinical outcomes were determined. For the non-randomized studies, the risk of bias assessment tool was used to assess the methodological quality of the included publications. The Mantel-Haenszel random-effects model of the RevMan software (Cochrane) and the inverse variance method were used to analyse binary end points and conti

SUBMITTER: Jung DH 

PROVIDER: S-EPMC7055310 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature