When it hurts even more: The neural dynamics of pain and interpersonal emotions.

ABSTRACT:

Objective

Chronic pain is highly prevalent among patients with mood, anxiety, personality, and somatic symptom disorders; and patients with chronic pain often suffer from persistent interpersonal distress. However, the neural mechanisms underlying this phenomenon and its possible role in the etiology of chronic pain are not yet understood. Based on our Developmental Theory of Centralized/Somatoform Pain, and prior research suggesting the existence of a shared neural system subserving interpersonal emotions and pain, we aimed to identify the neural basis for modulation of pain by feelings of interpersonal rejection and the role of the early interpersonal environment in development of this shared neural system.

Methods

During fMRI scanning, 22 healthy participants received mod

SUBMITTER: Landa A 

PROVIDER: S-EPMC7055518 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature