Statins for Smith-Lemli-Opitz syndrome.

ABSTRACT: This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: 1. To evaluate the efficacy of statin therapy in reducing the frequency or severity of the neurobehavioral abnormalities seen in people with SLOS (e.g. aggression, anxiety, irritability, self-mutilation, autistic behaviors, sleep disturbances, etc.) (Wassif 2017). 2. To evaluate the potential effects of statin therapy on survival.

SUBMITTER: Ballout RA 

PROVIDER: S-EPMC7055734 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature