Proton MR spectroscopy of Sjogren-Larsson's syndrome.

ABSTRACT: We performed single-voxel proton MR spectroscopy (1H-MRS) in two children with Sjögren-Larsson's syndrome (SLS). Both patients showed two abnormal spectral peaks at 1.3 ppm and 0.9 ppm that were obtained with short echo times. These two abnormal spectral peaks were seen in high-intensity areas on T2-weighted images and also in basal ganglia of normal intensities. 1H-MRS may be useful for establishing the diagnosis and investigating the natural history of SLS, and for evaluating the efficacy of therapeutic approaches to SLS.

SUBMITTER: Mano T 

PROVIDER: S-EPMC7056198 | biostudies-literature | 1999 Oct

REPOSITORIES: biostudies-literature