Cognitive Improvement After Kidney Transplantation Is Associated With Structural and Functional Changes on MRI.

ABSTRACT:

Background

Several studies have reported improved cognitive outcomes after kidney transplantation, but most studies either did not include controls or lacked extensive neuroimaging. In addition, there is uncertainty whether kidney donation is a safe procedure in terms of cognitive outcomes.

Methods

We prospectively studied neurocognitive function in kidney transplant recipients. The primary outcome was change in neurocognitive function after 1 year compared with baseline, which was evaluated using the Amsterdam Neuropsychological Task battery and verbal fluency tests. Secondary outcomes included changes in depression and anxiety (measured by the Hospital Anxiety and Depression scale) and changes in fatigue (measured by the Checklist for Individual Strength). We included kidn

SUBMITTER: van Sandwijk MS 

PROVIDER: S-EPMC7056275 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature