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Live births after oocyte in vitro maturation with a prematuration step in women with polycystic ovary syndrome.


ABSTRACT: PURPOSE:Standard oocyte in vitro maturation (IVM) usually results in lower pregnancy rates than in vitro fertilization (IVF). IVM preceded by a prematuration step improves the acquisition of oocyte developmental competence and can enhance embryo quality (EQ). This study evaluated the effectiveness of a biphasic culture system incorporating prematuration and IVM steps (CAPA-IVM) versus standard IVM in women with polycystic ovarian morphology (PCOM). METHODS:Eighty women (age

SUBMITTER: Vuong LN 

PROVIDER: S-EPMC7056678 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature

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Live births after oocyte in vitro maturation with a prematuration step in women with polycystic ovary syndrome.

Vuong Lan N LN   Le Anh H AH   Ho Vu N A VNA   Pham Toan D TD   Sanchez Flor F   Romero Sergio S   De Vos Michel M   Ho Tuong M TM   Gilchrist Robert B RB   Smitz Johan J  

Journal of assisted reproduction and genetics 20200104 2


<h4>Purpose</h4>Standard oocyte in vitro maturation (IVM) usually results in lower pregnancy rates than in vitro fertilization (IVF). IVM preceded by a prematuration step improves the acquisition of oocyte developmental competence and can enhance embryo quality (EQ). This study evaluated the effectiveness of a biphasic culture system incorporating prematuration and IVM steps (CAPA-IVM) versus standard IVM in women with polycystic ovarian morphology (PCOM).<h4>Methods</h4>Eighty women (age < 38 y  ...[more]

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