Terlipressin for the treatment of septic shock in adults: a systematic review and meta-analysis.

ABSTRACT:

Background

Catecholamines are the first-line vasopressors used in patients with septic shock. However, the search for novel drug candidates is still of great importance due to the development of adrenergic hyposensitivity accompanied by a decrease in catecholamine activity. Terlipressin (TP) is a synthetic vasopressin analogue used in the management of patients with septic shock. In the current study, we aimed to compare the effects of TP and catecholamine infusion in treating septic shock patients.

Methods

A systematic review and meta-analysis was conducted by searching articles published in PUBMED, EMBASE, and the Cochrane Central Register of Controlled Trials between inception and July 2018. We only selected randomized controlled trials evaluating the use of TP and catech

SUBMITTER: Huang L 

PROVIDER: S-EPMC7057452 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature