Lymph node metastasis in young and middle-aged papillary thyroid carcinoma patients: a SEER-based cohort study.

ABSTRACT: BACKGROUND:Lymph node metastasis (LNM) occurs frequently in young papillary thyroid carcinoma (PTC) patients, though the mortality rates are low. We aimed to analyze the relationship between age at diagnosis and LNM in PTC at a population level to elucidate the clinical behavior of PTC. METHODS:Data of adult patients with surgically treated PTC and follicular thyroid carcinoma (FTC) were identified from the Surveillance, Epidemiology, and End Results (SEER) database (2004-2015) to investigate the relationship between age and clinical characteristics by curve estimation. The adjusted odds ratio of age and LNM rate were determined. RESULTS:A total of 50,347 PTC (48,166) and FTC (2181) (median age: 45 and 50 years, respectively) patients met the inclusion criteria; 44.5% of those with PTC (21

SUBMITTER: Liu Y 

PROVIDER: S-EPMC7057480 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature