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Sarcopenia as a predictor of mortality in women with breast cancer: a meta-analysis and systematic review.


ABSTRACT: BACKGROUND:Breast cancer is the most commonly diagnosed cancer and the leading cause of cancer death in women worldwide. Recently, studies have been published with inconsistent findings regarding whether sarcopenia is a risk factor for mortality in breast cancer patients. Therefore, the aim of this systematic review and meta-analysis was to systematically assess and quantify sarcopenia as a risk factor for mortality in breast cancer patients. METHODS:In a systematic literature review of PubMed, EMBASE, and the Cochrane CENTRAL Library, we searched for observational studies written in English (from database inception until April 30, 2019) that reported an association between sarcopenia and breast cancer in women who were 18 years or older. RESULTS:A total of six studies (5497 participants)

SUBMITTER: Zhang XM 

PROVIDER: S-EPMC7057618 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature