A comparison of three column agglutination tests for red blood cell alloantibody identification.

ABSTRACT:

Objective

Commercial kits of column tests for pre-transfusion testing have progressively replaced conventional tube tests in most laboratories. Aim of this study was to compare three commercial test cell panels for the identification of irregular red blood cell (RBC) alloantibodies. Overall, 44 samples with a positive indirect antiglobulin test (IAT) by routine testing were used for comparison of following panels: Ortho RESOLVE^® panelC (Ortho Clinical Diagnostics (OCD), Milan, Italy), ID-DiaPanel(-P) (Bio-Rad Laboratories, CA, USA) and Identisera Diana(P) (Grifols, Barcelona, Spain). Column agglutination techniques were used, with microtubes containing either microgel (Bio-Rad/Grifols) or glass bead microparticles (Ortho).

Results

Alloantibody identification was p

SUBMITTER: Blomme S 

PROVIDER: S-EPMC7057655 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature