Photobactericidal activity activated by thiolated gold nanoclusters at low flux levels of white light.

ABSTRACT: The emergence of antibiotic resistant bacteria is a major threat to the practice of modern medicine. Photobactericidal agents have obtained significant attention as promising candidates to kill bacteria, and they have been extensively studied. However, to obtain photobactericidal activity, an intense white light source or UV-activation is usually required. Here we report a photobactericidal polymer containing crystal violet (CV) and thiolated gold nanocluster ([Au₂₅(Cys)₁₈]) activated at a low flux levels of white light. It was shown that the polymer encapsulated with CV do not have photobactericidal activity under white light illumination of an average 312 lux. However, encapsulation of [Au₂₅(Cys)₁₈] and CV into the polymer activates potent phot

SUBMITTER: Hwang GB 

PROVIDER: S-EPMC7057968 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature