Unknown

Dataset Information

0

The identification of a CD47-blocking "hotspot" and design of a CD47/PD-L1 dual-specific antibody with limited hemagglutination.

ABSTRACT:

SUBMITTER: Shi R 

PROVIDER: S-EPMC7058617 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

The identification of a CD47-blocking "hotspot" and design of a CD47/PD-L1 dual-specific antibody with limited hemagglutination.

Shi Rui R   Chai Yan Y   Duan Xiaomin X   Bi Xiaoshan X   Huang Qingrui Q   Wang Qihui Q   Tan Shuguang S   Gao George F GF   Zhu Jianhua J   Yan Jinghua J  

Signal transduction and targeted therapy 20200306 1

Similar Datasets

Unknown Tumor-selective blockade of CD47 signaling with a CD47/PD-L1 bispecific antibody for enhanced anti-tumor activity and limited toxicity.
| S-EPMC10991320 | biostudies-literature
Unknown Blockade of dual immune checkpoint inhibitory signals with a CD47/PD-L1 bispecific antibody for cancer treatment.
| S-EPMC9800731 | biostudies-literature
Unknown IMM2520, a novel anti-CD47/PD-L1 bispecific antibody for cancer immune therapy.
| S-EPMC11564011 | biostudies-literature
Unknown S216: CD47/PD-L1 BISPECIFIC ANTIBODY (IBI322) IN ANTI-PD-1 OR PD-L1 TREATMENT-RESISTANT CLASSICAL HODGKIN LYMPHOMA: A PHASE I STUDY
| S-EPMC10428475 | biostudies-literature
Unknown Dual blockage of both PD-L1 and CD47 enhances immunotherapy against circulating tumor cells.
| S-EPMC6418176 | biostudies-literature
Unknown Simultaneous blocking of CD47 and PD-L1 increases innate and adaptive cancer immune responses and cytokine release.
| S-EPMC6491392 | biostudies-literature
Transcriptomics Dual checkpoint blockade of CD47 and PD-L1 using a novel affinity-tuned bispecific antibody maximizes anti-tumor immunity
2021-10-15 | GSE180297 | GEO
Unknown Discovery of a novel small molecule as CD47/SIRPα and PD-1/PD-L1 dual inhibitor for cancer immunotherapy.
| S-EPMC10926604 | biostudies-literature
Unknown CD47-blocking antibody confers metabolic benefits against obesity.
| S-EPMC12147847 | biostudies-literature
Transcriptomics Dual checkpoint blockade of CD47 and PD-L1 using a novel affinity-tuned bispecific antibody maximizes anti-tumor immunity (NanoString)
2021-10-13 | GSE177053 | GEO