Association between multivitamin supplementation and mortality among patients with Ebola virus disease: An international multisite cohort study.

ABSTRACT:

Introduction

Micronutrient supplementation is recommended in Ebola Virus Disease (EVD) care; however, there is limited data on its therapeutic effects.

Methods

This retrospective cohort study included patients with EVD admitted to five Ebola Treatment Units (ETU) in Sierra Leone and Liberia during September 2014 to December 2015. A uniform protocol was used to guide ETU care, however, due to supply limitations, only a subset of patients received multivitamins. Data on demographics, clinical characteristics, and laboratory testing was collected. The outcome of interest was facility-based mortality and the primary predictor was multivitamin supplementation initiated within 48 h of admission. The multivitamin formulations included: thiamine, riboflavin, niacin and vitamins A, C

SUBMITTER: Yam D 

PROVIDER: S-EPMC7058859 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature