Differential Reorganization of SMA Subregions After Stroke: A Subregional Level Resting-State Functional Connectivity Study.

ABSTRACT: Background and Purpose: The human supplementary motor area (SMA) contains two functional subregions of the SMA proper and preSMA; however, the reorganization patterns of the two SMA subregions after stroke remain uncertain. Meanwhile, a focal subcortical lesion may affect the overall functional reorganization of brain networks. We sought to identify the differential reorganization of the SMA subregions after subcortical stroke using the resting-state functional connectivity (rsFC) analysis. Methods: Resting-state functional MRI was conducted in 25 patients with chronic capsular stroke exhibiting well-recovered global motor function (Fugl-Meyer score >90). The SMA proper and preSMA were identified by the rsFC-based parcellation, and the rsFCs of each SMA subregion were compared between stro

SUBMITTER: Liu H 

PROVIDER: S-EPMC7059000 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature