Elevated central venous pressure is associated with increased mortality and acute kidney injury in critically ill patients: a meta-analysis.

ABSTRACT: BACKGROUND:The association of central venous pressure (CVP) and mortality and acute kidney injury (AKI) in critically ill adult patients remains unclear. We performed a meta-analysis to determine whether elevated CVP is associated with increased mortality and AKI in critically ill adult patients. METHODS:We searched PubMed and Embase through June 2019 to identify studies that investigated the association between CVP and mortality and/or AKI in critically ill adult patients admitted into the intensive care unit. We calculated the summary odds ratio (OR) and 95% CI using a random-effects model. RESULTS:Fifteen cohort studies with a broad spectrum of critically ill patients (mainly sepsis) were included. On a dichotomous scale, elevated CVP was associated with an increased risk of mortality (

SUBMITTER: Chen CY 

PROVIDER: S-EPMC7059303 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature