Binding Options for the Small Subunit-Like Domain of Cyanobacteria to Rubisco.

ABSTRACT: Two proteins found in cyanobacteria contain a C-terminal domain with homology to the small subunit of rubisco (RbcS). These small subunit-like domains (SSLDs) are important features of CcmM, a protein involved in the biogenesis of carboxysomes found in all β-cyanobacteria, and a rubisco activase homolog [activase-like protein of cyanobacteria (ALC)] found in over a third of sequenced cyanobacterial genomes. Interaction with rubisco is crucial to the function of CcmM and is believed to be important to ALC as well. In both cases, the SSLD aggregates rubisco, and this nucleation event may be important in regulating rubisco assembly and activity. Recently, two independent studies supported the conclusion that the SSLD of CcmM binds equatorially to L₈S₈ holoenzymes of rubi

SUBMITTER: Rohnke BA 

PROVIDER: S-EPMC7059596 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature