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Oxcarbazepine add-on for drug-resistant focal epilepsy.


ABSTRACT:

SUBMITTER: Bresnahan R 

PROVIDER: S-EPMC7059897 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature

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Oxcarbazepine add-on for drug-resistant focal epilepsy.

Bresnahan Rebecca R   Atim-Oluk Margaret M   Marson Anthony G AG  

The Cochrane database of systematic reviews 20200304


<h4>Background</h4>Epilepsy is a common neurological disorder. In approximately 30% of epilepsy cases, seizures are uncontrolled by one antiepileptic drug (AED). These people require treatment with a combination of multiple AEDs and are described as having drug-resistant epilepsy. Oxcarbazepine is a keto-analogue of carbamazepine, an established AED, and can be used as an add-on treatment for drug-resistant epilepsy.<h4>Objectives</h4>To assess the efficacy and tolerability of oxcarbazepine as a  ...[more]

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