FCM_PASS Software Aids Extracellular Vesicle Light Scatter Standardization.

ABSTRACT: The study of extracellular vesicles (EVs) is a rapidly growing field due to their great potential in many areas of clinical medicine including diagnostics, prognostics, theranostics, and therapeutics. Flow cytometry is currently one of the most popular methods of analyzing EVs due to it being a high-throughput, multiparametric technique, that is readily available in the majority of research labs. Despite its wide use, few commercial flow cytometers are designed specifically for the detection of EVs. Many flow cytometers used for EV analysis are working at their detection limits and are unable to detect the majority of EVs. Currently, very little standardization exists for EV flow cytometry, which is an issue because flow cytometers vary considerably in the way they collect scattered or flu

SUBMITTER: Welsh JA 

PROVIDER: S-EPMC7061335 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature