Anticoagulants' Safety and Effectiveness in General Practice: A Nationwide Prospective Cohort Study.

ABSTRACT:

Purpose

Most real-world studies on anticoagulants have been based on health insurance databases or performed in secondary care. The aim of this study was to compare safety and effectiveness between patients treated with vitamin K antagonists (VKAs) and patients treated with direct oral anticoagulants (DOACs) in a general practice setting.

Methods

The CACAO study (Comparison of Accidents and their Circumstances with Oral Anticoagulants) is a multicenter prospective cohort study conducted among ambulatory patients taking an oral anticoagulant. Participants were patients from the study's cross-sectional phase receiving oral anticoagulants because of nonvalvular atrial fibrillation, for secondary prevention of venous thromboembolism, or both. They were followed as usual for 1 ye

SUBMITTER: Frappe P 

PROVIDER: S-EPMC7062492 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature