WebGQT: A Shiny Server for Genotype Query Tools for Model-Based Variant Filtering.

ABSTRACT:

Summary

Genotype Query Tools (GQT) were developed to discover disease-causing variations from billions of genotypes and millions of genomes, processes data at substantially higher speed over other existing methods. While GQT has been available to a wide audience as command-line software, the difficulty of constructing queries among non-IT or non-bioinformatics researchers has limited its applicability. To overcome this limitation, we developed webGQT, an easy-to-use tool with a graphical user interface. With pre-built queries across three modules, webGQT allows for pedigree analysis, case-control studies, and population frequency studies. As a package, webGQT allows researchers with less or no applied bioinformatics/IT experience to mine potential disease-causing variants from bill

SUBMITTER: Arumilli M 

PROVIDER: S-EPMC7063093 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature