Non-communicable respiratory disease and air pollution exposure in Malawi: a prospective cohort study.

ABSTRACT:

Rationale

There are no population-based studies from sub-Saharan Africa describing longitudinal lung function in adults.

Objectives

To explore the lung function trajectories and their determinants, including the effects of air pollution exposures and the cleaner-burning biomass-fuelled cookstove intervention of the Cooking and Pneumonia Study (CAPS), in adults living in rural Malawi.

Methods

We assessed respiratory symptoms and exposures, spirometry and measured 48-hour personal exposure to fine particulate matter (PM_2.5) and carbon monoxide (CO), on three occasions over 3 years. Longitudinal data were analysed using mixed-effects modelling by maximum likelihood estimation.

Measurements and main results

We recruited 1481 adults, mean (SD) age 43.8 (1

SUBMITTER: Rylance S 

PROVIDER: S-EPMC7063402 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature