Optimising pharmacotherapy in older cancer patients with polypharmacy.

ABSTRACT:

Objective

Polypharmacy is frequent among older cancer patients and increases the risk of potential drug-related problems (DRPs). DRPs are associated with adverse drug events, drug-drug interactions and hospitalisations. Since no standardised polypharmacy assessment methods for oncology patients exist, we aimed to develop one that can be integrated into routine care.

Methods

Based on the Systematic Tool to Reduce Inappropriate Prescribing (STRIP), we developed OncoSTRIP, which includes a polypharmacy anamnesis, a concise geriatric assessment, a polypharmacy analysis taking life expectancy into account and an optimised treatment plan. Patients ≥65 years with ≥5 chronic drugs visiting our outpatient oncology clinic were eligible for the polypharmacy assessment.

Results

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SUBMITTER: Vrijkorte E 

PROVIDER: S-EPMC7063689 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature