Atypical Hemolytic Uremic Syndrome With the p.Ile1157Thr C3 Mutation Successfully Treated With Plasma Exchange and Eculizumab: A Case Report.

ABSTRACT: To describe a case of atypical hemolytic uremic syndrome induced by influenza A infection with the p.Ile1157Thr C3 mutation.

Data sources

Clinical observations of a patient.

Study selection

Case reports.

Data extraction

Data extracted from medical records, after patient's consent.

Data synthesis

Four days prior to presentation to our hospital, a 16-year-old adolescent had a fever and arthralgia with hematuria. He was found to be positive for type A influenza and prescribed oseltamivir and acetaminophen by a primary-care physician. A bleeding tendency and purpura in the extremities and on the trunk developed; therefore, he was transferred to Chiba University Hospital. Hematology revealed severe thrombocytopenia, hyperbilirubinemia, and acute kidney injury. Aspart

SUBMITTER: Saito D 

PROVIDER: S-EPMC7063875 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature