Independent Association of Glucose Variability With Hospital Mortality in Adult Intensive Care Patients: Results From the Australia and New Zealand Intensive Care Society Centre for Outcome and Resource Evaluation Binational Registry.

ABSTRACT: Wide variations in blood glucose excursions in critically ill patients may influence adverse outcomes such as hospital mortality. However, whether blood glucose variability is independently associated with mortality or merely captures the excess risk attributable to hyperglycemic and hypoglycemic episodes is not established. We investigated whether blood glucose variability independently predicted hospital mortality in nonhyperglycemic critical care patients.

Design

Retrospective, registry data analyses of outcomes.

Setting

Large, binational registry (Australia and New Zealand Intensive Care Society Centre for Outcome and Resource Evaluation Adult Patient Database repository) of 176 ICUs across Australia and New Zealand.

Patients

We used 10-year data on nonhyperglycemi

SUBMITTER: Kulkarni H 

PROVIDER: S-EPMC7063954 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature