Innovative Multiparametric Characterization of Carotid Plaque Vulnerability by Ultrasound.

ABSTRACT:

Objective

The degree of stenosis of a carotid plaque is a well-established risk factor for ischemic stroke. Nevertheless, the risk of ipsilateral stroke in asymptomatic carotid stenosis remains low and new imaging markers are needed to better target which patients would benefit most from endarterectomy or intensive medical therapy. Ultrafast ultrasound imaging offers parameters helping at characterizing the carotid plaque by shear wave elastography and Ultrafast Doppler (UFD). We aimed at using these techniques to characterize 3 different ultrasound biomarkers: plaque stiffness heterogeneity, wall shear stress (WSS) and intraplaque micro-flows and to correlate these biomarkers with findings on computed tomography angiography (CTA) and the pathological examination.

Methods

We

SUBMITTER: Goudot G 

PROVIDER: S-EPMC7064056 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature