Ontology highlight
ABSTRACT:
SUBMITTER: Shen J
PROVIDER: S-EPMC7064516 | biostudies-literature | 2020 Mar
REPOSITORIES: biostudies-literature
Shen Jie J Qi Liang L Zou Zhengyun Z Du Juan J Kong Weiwei W Zhao Lianjun L Wei Jia J Lin Ling L Ren Min M Liu Baorui B
Scientific reports 20200310 1
Hepatocellular carcinoma (HCC) is a common malignant tumor in China. In the present study, we aimed to construct and verify a prediction model of recurrence in HCC patients using databases (TCGA, AMC and Inserm) and machine learning methods and obtain the gene signature that could predict early relapse of HCC. Statistical methods, such as feature selection, survival analysis and Chi-Square test in R software, were used to analyze and select mutant genes related to disease free survival (DFS), ra ...[more]