Modified frailty index predicts postoperative outcomes in older gastrointestinal cancer patients.

ABSTRACT:

Background and objectives

Frailty disproportionately impacts older patients with gastrointestinal cancer, rendering them at increased risk for poor outcomes. A frailty index may aid in preoperative risk stratification. We hypothesized that high modified frailty index (mFI) scores are associated with adverse outcomes after tumor resection in older, gastrointestinal cancer patients.

Methods

Patients (60-90 years old) who underwent gastrointestinal tumor resection were identified in the 2005-2012 NSQIP Participant Use File. mFI was defined by 11 previously described, preoperative variables. Frailty was defined by an mFI score >0.27. The postoperative course was evaluated using univariate and multivariate analysis.

Results

41 455 patients (mean age 72.4 years, 47.4% femal

SUBMITTER: Vermillion SA 

PROVIDER: S-EPMC7064809 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature