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Postpartum hemorrhage care bundles to improve adherence to guidelines: A WHO technical consultation.


ABSTRACT:

Objective

To systematically develop evidence-based bundles for care of postpartum hemorrhage (PPH).

Methods

An international technical consultation was conducted in 2017 to develop draft bundles of clinical interventions for PPH taken from the WHO's 2012 and 2017 PPH recommendations and based on the validated "GRADE Evidence-to-Decision" framework. Twenty-three global maternal-health experts participated in the development process, which was informed by a systematic literature search on bundle definitions, designs, and implementation experiences. Over a 6-month period, the expert panel met online and via teleconferences, culminating in a 2-day in-person meeting.

Results

The consultation led to the definition of two care bundles for facility implementation. The "first response to PPH bundle" comprises uterotonics, isotonic crystalloids, tranexamic acid, and uterine massage. The "response to refractory PPH bundle" comprises compressive measures (aortic or bimanual uterine compression), the non-pneumatic antishock garment, and intrauterine balloon tamponade (IBT). Advocacy, training, teamwork, communication, and use of best clinical practices were defined as PPH bundle supporting elements.

Conclusion

For the first response bundle, further research should assess its feasibility, acceptability, and effectiveness; and identify optimal implementation strategies. For the response to refractory bundle, further research should address pending controversies, including the operational definition of refractory PPH and effectiveness of IBT devices.

SUBMITTER: Althabe F 

PROVIDER: S-EPMC7064978 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature

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Publications

Postpartum hemorrhage care bundles to improve adherence to guidelines: A WHO technical consultation.

Althabe Fernando F   Therrien Michelle N S MNS   Pingray Veronica V   Hermida Jorge J   Gülmezoglu Ahmet M AM   Armbruster Deborah D   Singh Neelima N   Guha Moytrayee M   Garg Lorraine F LF   Souza Joao P JP   Smith Jeffrey M JM   Winikoff Beverly B   Thapa Kusum K   Hébert Emmanuelle E   Liljestrand Jerker J   Downe Soo S   Garcia Elorrio Ezequiel E   Arulkumaran Sabaratnam S   Byaruhanga Emmanuel K EK   Lissauer David M DM   Oguttu Monica M   Dumont Alexandre A   Escobar Maria F MF   Fuchtner Carlos C   Lumbiganon Pisake P   Burke Thomas F TF   Miller Suellen S  

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20191223 3


<h4>Objective</h4>To systematically develop evidence-based bundles for care of postpartum hemorrhage (PPH).<h4>Methods</h4>An international technical consultation was conducted in 2017 to develop draft bundles of clinical interventions for PPH taken from the WHO's 2012 and 2017 PPH recommendations and based on the validated "GRADE Evidence-to-Decision" framework. Twenty-three global maternal-health experts participated in the development process, which was informed by a systematic literature sea  ...[more]

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