Reduced radiation-induced toxicity by using proton therapy for the treatment of oropharyngeal cancer.

ABSTRACT: Patients with squamous cell carcinoma of the oropharynx are generally treated with (chemo) radiation. Patients with oropharyngeal cancer have better survival than patients with squamous cell carcinoma of other head and neck subsites, especially when related to human papillomavirus. However, radiotherapy results in a substantial percentage of survivors suffering from significant treatment-related side-effects. Late radiation-induced side-effects are mostly irreversible and may even be progressive, and particularly xerostomia and dysphagia affect health-related quality of life. As the risk of radiation-induced side-effects highly depends on dose to healthy normal tissues, prevention of radiation-induced xerostomia and dysphagia and subsequent improvement of health-relatedquality of life can

SUBMITTER: Meijer TWH 

PROVIDER: S-EPMC7066974 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature