Trauma reactivation under propranolol among traumatized Syrian refugee children: preliminary evidence regarding efficacy.

ABSTRACT: Background: There is a dearth of therapeutic solutions for traumatized young patients. Trauma reactivation conducted under the influence of the reconsolidation blocker propranolol (Reconsolidation Therapy) is a simple, cost-effective treatment option that has some promising initial results in adults suffering from posttraumatic stress disorder (PTSD). Objective: To explore the usefulness of this novel treatment in children. The primary outcome was the reduction of PTSD symptoms at the end of treatment, while secondary outcomes included reduction in anxiety and in depressive symptoms. Method: An open-label clinical trial was conducted in a refugee camp in Syria, investigating the safety and efficacy of this therapeutic strategy in 117 children suffering from enduring PT

SUBMITTER: Thierree S 

PROVIDER: S-EPMC7067198 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature