Both clinical and environmental Caulobacter species are virulent in the Galleria mellonella infection model.

ABSTRACT: The Caulobacter genus, including the widely-studied model organism Caulobacter crescentus, has been thought to be non-pathogenic and thus proposed as a bioengineering vector for various environmental remediation and medical purposes. However, Caulobacter species have been implicated as the causative agents of several hospital-acquired infections, raising the question of whether these clinical isolates represent an emerging pathogenic species or whether Caulobacters on whole possess previously-unappreciated virulence capability. Given the proposed environmental and medical applications for C. crescentus, understanding the potential pathogenicity of this bacterium is crucial. Consequently, we sequenced a clinical Caulobacter isolate to determine if it has acquired novel virulence determinant

SUBMITTER: Moore GM 

PROVIDER: S-EPMC7067423 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature