Long-term, disease-specific outcomes of thymic malignancies presenting with de novo pleural metastasis.

ABSTRACT:

Objective

Treatment of patients with thymic malignancies metastatic to the pleura or pericardium is challenging, and benefits of aggressive treatment are unclear. We sought to characterize the long-term outcomes in this population.

Methods

We retrospectively identified patients who underwent resection for de novo thymic malignancies metastatic to the pleura between May 1997 and December 2017. Patients with pleural recurrence after prior thymectomy were excluded. Patient demographics, perioperative treatments, pathologic findings, and postoperative outcomes were collected. Descriptive statistics and Kaplan-Meier analyses were performed.

Results

Seventy-two patients were included (median age, 51 years [range 25-80]; 36/72 women [50%]). Pathologic diagnosis was thymoma i

SUBMITTER: Choe G 

PROVIDER: S-EPMC7067622 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature