No changes in gut microbiota after two-week sleep extension in chronically sleep-deprived individuals.

ABSTRACT:

Background

Gut microbiota has been linked to obesity and glucose metabolism. Insufficient sleep is also known to be associated with insulin resistance, and sleep extension was reported to improve glucose metabolism in short sleepers. This study aimed to explore whether sleep extension was associated with changes in gut microbiota and whether there was a relationship with glucose parameters.

Methods

We performed a secondary analysis of eight short-seeping but otherwise healthy subjects who participated in a cross over study of two-week home sleep extension and two weeks of habitual sleep. After each sleep condition, stool samples were collected and glucose parameters were obtained. Stool DNA extraction was performed and 16S rRNA was sequenced by MiSeq™. The resulting sequence

SUBMITTER: Reutrakul S 

PROVIDER: S-EPMC7067631 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature