Tissue Distribution and Immunomodulation in Channel Catfish (Ictalurus punctatus) Following Dietary Exposure to Polychlorinated Biphenyl Aroclors and Food Deprivation.

ABSTRACT: Although most countries banned manufacturing of polychlorinated biphenyls (PCBs) over 40 years ago, PCBs remain a global concern for wildlife and human health due to high bioaccumulation and biopersistance. PCB uptake mechanisms have been well studied in many taxa; however, less is known about depuration rates and how post-exposure diet can influence PCB concentrations and immune response in fish and wildlife populations. In a controlled laboratory environment, we investigated the influence of subchronic dietary exposure to two PCB Aroclors and food deprivation on tissue-specific concentrations of total PCBs and PCB homologs and innate immune function in channel catfish (Ictalurus punctatus). Overall, we found that the concentration of total PCBs and PCB homologs measured in whole body, fi

SUBMITTER: White SL 

PROVIDER: S-EPMC7068257 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature