Ontology highlight
ABSTRACT:
SUBMITTER: Jaitin DA
PROVIDER: S-EPMC7068689 | biostudies-literature | 2019 Jul
REPOSITORIES: biostudies-literature
Cell 20190627 3
Immune cells residing in white adipose tissue have been highlighted as important factors contributing to the pathogenesis of metabolic diseases, but the molecular regulators that drive adipose tissue immune cell remodeling during obesity remain largely unknown. Using index and transcriptional single-cell sorting, we comprehensively map all adipose tissue immune populations in both mice and humans during obesity. We describe a novel and conserved Trem2<sup>+</sup> lipid-associated macrophage (LAM ...[more]