Dissociated neuronal phase- and amplitude-coupling patterns in the human brain.

ABSTRACT: Coupling of neuronal oscillations may reflect and facilitate the communication between neuronal populations. Two primary neuronal coupling modes have been described: phase-coupling and amplitude-coupling. Theoretically, both coupling modes are independent, but so far, their neuronal relationship remains unclear. Here, we combined MEG, source-reconstruction and simulations to systematically compare cortical amplitude-coupling and phase-coupling patterns in the human brain. Importantly, we took into account a critical bias of amplitude-coupling measures due to phase-coupling. We found differences between both coupling modes across a broad frequency range and most of the cortex. Furthermore, by combining empirical measurements and simulations we ruled out that these results were caused by met

SUBMITTER: Siems M 

PROVIDER: S-EPMC7068703 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature