The relationship between symptom burden and systemic inflammation differs between male and female athletes following concussion.

ABSTRACT:

Background

Inflammation appears to be an important component of concussion pathophysiology. However, its relationship to symptom burden is unclear. Therefore, the purpose of this study was to evaluate the relationship between symptoms and inflammatory biomarkers measured in the blood of male and female athletes following a sport-related concussion (SRC).

Results

Forty athletes (n = 20 male, n = 20 female) from nine interuniversity sport teams at a single institution provided blood samples within one week of an SRC. Twenty inflammatory biomarkers were quantitated by immunoassay. The Sport Concussion Assessment Tool version 5 (SCAT-5) was used to evaluate symptoms. Partial least squares (PLS) analyses were used to evaluate the relationship(s) between biomarkers and symptoms. I

SUBMITTER: Di Battista AP 

PROVIDER: S-EPMC7068899 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature