Genomic and transcriptomic analysis of Candida intermedia reveals the genetic determinants for its xylose-converting capacity.

ABSTRACT:

Background

An economically viable production of biofuels and biochemicals from lignocellulose requires microorganisms that can readily convert both the cellulosic and hemicellulosic fractions into product. The yeast Candida intermedia displays a high capacity for uptake and conversion of several lignocellulosic sugars including the abundant pentose d-xylose, an underutilized carbon source since most industrially relevant microorganisms cannot naturally ferment it. Thus, C. intermedia constitutes an important source of knowledge and genetic information that could be transferred to industrial microorganisms such as Saccharomyces cerevisiae to improve their capacity to ferment lignocellulose-derived xylose.

Results

To understand the genetic determinants tha

SUBMITTER: Geijer C 

PROVIDER: S-EPMC7068945 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature