Effectiveness of pharmacological agents for the treatment of non-infectious scleritis: a systematic review protocol.

ABSTRACT:

Background

Non-infectious scleritis is a potentially sight-threatening condition in which the sclera, the white outer layer of the eye, becomes inflamed. Whilst scleritis can be infective, the majority of cases are due to non-infectious causes, often occurring in association with an underlying systemic autoimmune or auto-inflammatory condition. Thorough systemic work-up is crucial to identify disease aetiology and exclude infection; however, a significant proportion of disease remains idiopathic with the underlying cause unknown. Non-infectious scleritis is normally managed with systemic corticosteroid and immunosuppression, yet there is no widely agreed consensus on the most appropriate therapy, and no national or international guidelines exist for treatment of non-infectious scle

SUBMITTER: Ingaralingam S 

PROVIDER: S-EPMC7068966 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature