Frailty assessment and risk prediction by GRACE score in older patients with acute myocardial infarction.

ABSTRACT:

Background

Risk prediction after myocardial infarction is often complex in older patients. The Global Registry of Acute Coronary Events (GRACE) model includes clinical parameters and age, but not frailty. We hypothesised that frailty would enhance the prognostic properties of GRACE.

Methods

We performed a prospective observational cohort study in two independent cardiology units: the Royal Infirmary of Edinburgh, UK (primary cohort) and the South Yorkshire Cardiothoracic Centre, Sheffield, UK (external validation). The study sample included 198 patients ≥65 years old hospitalised with type 1 myocardial infarction (primary cohort) and 96 patients ≥65 years old undergoing cardiac catheterisation for myocardial infarction (external validation). Frailty was assessed using the Cl

SUBMITTER: Anand A 

PROVIDER: S-EPMC7069195 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature