E. coli "super-contaminates" narrow ducts fostered by broad run-time distribution.

ABSTRACT: One notable feature of bacterial motion is their ability to swim upstream along corners and crevices, by leveraging hydrodynamic interactions. This motion through anatomic ducts or medical devices might be at the origin of serious infections. However, it remains unclear how bacteria can maintain persistent upstream motion while exhibiting run-and-tumble dynamics. Here, we demonstrate that Escherichia coli can travel upstream in microfluidic devices over distances of 15 mm in times as short as 15 min. Using a stochastic model relating the run times to the time that bacteria spend on surfaces, we quantitatively reproduce the evolution of the contamination profiles when considering a broad distribution of run times. The experimental data cannot be reproduced using the usually accepted exponen

SUBMITTER: Figueroa-Morales N 

PROVIDER: S-EPMC7069694 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature