The Addictions Neuroclinical Assessment Negative Emotionality Domain Among Treatment-Seekers with Alcohol Use Disorder: Construct Validity and Measurement Invariance.

ABSTRACT:

Background

The Addictions Neuroclinical Assessment (ANA), a framework for measuring heterogeneity in alcohol use disorder (AUD), focuses on 3 domains that reflect neurobiological dysfunction in addiction and correspond to the cycles of addiction: executive function, incentive salience, and negative emotionality. Kwako and colleagues (Am J Psychiatry 176:744, 2019) validated a 3-factor model of the ANA with neuropsychological and self-report indicators among treatment-seekers and non-treatment-seekers with and without AUD. The present analysis replicated and extended these findings in a treatment-seeking sample, focusing on the negative emotionality domain.

Methods

Participants (n = 563; 58.8% male; mean age = 34.3) were part of a multisite prospective study of individuals en

SUBMITTER: Votaw VR 

PROVIDER: S-EPMC7069798 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature