Association between Timing of Energy Intake and Insulin Sensitivity: A Cross-Sectional Study.

ABSTRACT: In addition to the caloric and macronutrient composition of meals, timing of energy consumption may be important for optimal glucose metabolism. Our goal was to examine whether the habitual timing of energy intake was associated with insulin sensitivity in healthy volunteers. Volunteers without diabetes aged 21-50 years completed a 3-day food diary and underwent an oral glucose tolerance test to estimate insulin sensitivity (n = 44). From the food diary, we calculated the proportions of the total energy and macronutrients consumed in the morning and evening, and the clock time at which 25%, 50% and 75% of total energy was consumed. A greater proportion of energy intake in the morning was significantly associated with higher insulin sensitivity estimated by Matsuda Index (B = 2.8 per 10%; 9

SUBMITTER: Rangaraj VR 

PROVIDER: S-EPMC7071301 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature