Postural Balance Effects Associated with 400, 4000 or 10,000 IU Vitamin D₃ Daily for Three Years: A Secondary Analysis of a Randomized Clinical Trial.

ABSTRACT: Vitamin D supplementation is proposed as a fall prevention strategy, as it may improve neuromuscular function. We examined whether three years of vitamin D supplementation (400, 4000 or 10,000 IU daily) affects postural sway in older adults. Three hundred and seventy-three non-osteoporotic, vitamin D-sufficient, community-dwelling healthy adults, aged 55-70 years, were randomized to 400 (n = 124), 4000 (n = 125) or 10,000 (n = 124) IU daily vitamin D₃ for three years. Sway index was assessed at baseline, 12-, 24- and 36-months using the Biosway machine. We tested participants under four conditions: eyes open or eyes closed with firm (EOFI, ECFI) or foam (EOFO, ECFO) surfaces. Secondary assessments examined sway in the anterior-posterior (AP) and medio-lateral (ML) directions. Li

SUBMITTER: Burt LA 

PROVIDER: S-EPMC7071365 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature