Evaluation of confounding in epidemiologic studies assessing alcohol consumption on the risk of ischemic heart disease.

ABSTRACT:

Background

Among different investigators studying the same exposures and outcomes, there may be a lack of consensus about potential confounders that should be considered as matching, adjustment, or stratification variables in observational studies. Concerns have been raised that confounding factors may affect the results obtained for the alcohol-ischemic heart disease relationship, as well as their consistency and reproducibility across different studies. Therefore, we assessed how confounders are defined, operationalized, and discussed across individual studies evaluating the impact of alcohol on ischemic heart disease risk.

Methods

For observational studies included in a recent alcohol-ischemic heart disease meta-analysis, we identified all variables adjusted, matched, or

SUBMITTER: Wallach JD 

PROVIDER: S-EPMC7071725 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature