Multiple association analysis of loci and candidate genes that regulate body size at three growth stages in Simmental beef cattle.

ABSTRACT:

Background

Body size traits as one of the main breeding selection criteria was widely used to monitor cattle growth and to evaluate the selection response. In this study, body size was defined as body height (BH), body length (BL), hip height (HH), heart size (HS), abdominal size (AS), and cannon bone size (CS). We performed genome-wide association studies (GWAS) of these traits over the course of three growth stages (6, 12 and 18 months after birth) using three statistical models, single-trait GWAS, multi-trait GWAS and LONG-GWAS. The Illumina Bovine HD 770 K BeadChip was used to identify genomic single nucleotide polymorphisms (SNPs) in 1217 individuals.

Results

In total, 19, 29, and 10 significant SNPs were identified by the three models, respectively. Among these, 21 gen

SUBMITTER: An B 

PROVIDER: S-EPMC7071762 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature