Selected neuropeptide genes show genetic differentiation between Africans and non-Africans.

ABSTRACT:

Background

Publicly available genome data provides valuable information on the genetic variation patterns across different modern human populations. Neuropeptide genes are crucial to the nervous, immune, endocrine system, and physiological homeostasis as they play an essential role in communicating information in neuronal functions. It remains unclear how evolutionary forces, such as natural selection and random genetic drift, have affected neuropeptide genes among human populations. To date, there are over 100 known human neuropeptides from the over 1000 predicted peptides encoded in the genome. The purpose of this study is to analyze and explore the genetic variation in continental human populations across all known neuropeptide genes by examining highly differentiated SNPs betwe

SUBMITTER: Tai KY 

PROVIDER: S-EPMC7071772 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature