Screening flexible sigmoidoscopy versus colonoscopy for reduction of colorectal cancer mortality.

ABSTRACT:

Purpose

Colonoscopy and flexible sigmoidoscopy are both recommended colorectal cancer (CRC) screening strategies, but their relative effectiveness is unclear. We sought to evaluate the ability of each of these two modalities to reduce CRC mortality.

Methods

We conducted a case-control study using the Surveillance, Epidemiology, and End Results (SEER)-Medicare database. Cases were persons aged 70-85 years who died of CRC and were matched to up to three non-CRC controls. Receipt of endoscopy was ascertained from Medicare claims and endoscopy indication assigned using a validated algorithm. Conditional logistic regression models were developed to estimate the association between screening colonoscopy or sigmoidoscopy and CRC mortality. We conducted secondary analyses by race, s

SUBMITTER: Ko CW 

PROVIDER: S-EPMC7071949 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature