Structural and Functional Comparison of Salmonella Flagellar Filaments Composed of FljB and FliC.

ABSTRACT: The bacterial flagellum is a motility organelle consisting of a long helical filament as a propeller and a rotary motor that drives rapid filament rotation to produce thrust. Salmonellaenterica serovar Typhimurium has two genes of flagellin, fljB and fliC, for flagellar filament formation and autonomously switches their expression at a frequency of 10^-3-10^-4 per cell per generation. We report here differences in their structures and motility functions under high-viscosity conditions. A Salmonella strain expressing FljB showed a higher motility than one expressing FliC under high viscosity. To examine the reasons for this motility difference, we carried out structural analyses of the FljB filament by electron cryomicroscopy and found

SUBMITTER: Yamaguchi T 

PROVIDER: S-EPMC7072241 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature